New: Calli Essentials Hand Sanitizer

Posted on March 30 2020

I have been a bit apprehensive to release my essential oil-based hand sanitizer for a few reasons, mainly because I did not want to appear that I was capitalizing on a situation and the other with my reluctance to put out a hand sanitizer with alcohol in it.

You may wonder why I am reluctant to produce a product with alcohol; it is because of the countless studies that have been done that show alcohol-based hand sanitizers are contributing to our resistance to certain bacterial strains amongst other things. Having said this the CDC and Health Canada are only recommending alcohol-based hand sanitizers, so we have decided to offer both alcohol and alcohol-free versions.

Because of the increasing resistance, many essential oils have been studied at minimal concentrations and shown to be effective against bacteria, fungal and viral strains. The essential oil blend in our hand sanitizer has collectively been shown to have an effect against 30 gram-positive and gram-negative bacteria strains, numerous viruses including H1N1 and numerous fungal strains. We have reviewed over 40 studies done on these oils that have been completed by many sources including the European Medicines Agency (EMA) Food and Agriculture Organization of the United Nations (FOA) and the World Health Organization (WHO).

Both our alcohol and alcohol-free versions have the same essential oil blend at the same concentration. The non-alcohol blend has tree tea hydrosol in its place. We leave the choice with you to decide which one is best. Alcohol does not impair the ability of the essential oils, it is, in fact, a carrier for them. 

We are only offering travel size options of these hand sanitizers at this time (supply constraints due in part to COVID 19). Please know that we are a small company without the benefit of large bulk purchases but have kept our price low and our profit minimum.


European Medicines Agency (EMA) Evaluation of Medicines for Human Use, Committee on herbal medicinal products (HMPC) (2010). Community herbal monograph on Rosmarinus officinalis l.,aetheroleum.

European Medicines Agency (EMA) Evaluation of Medicines for Human Use, Committee on herbal medicinal products (HMPC) (2011). Assessment report on Cinnamomum verum J. S. Presl, cortex and corticis aetheroleum.

Food and Agriculture Organization of the United Nations (FAO) and World Health Organization (WHO) (2003). Joint FAO/WHO Expert Committee on Food Additives (JECFA).

Friedman M., Henika P. R., & Mandrell R. E. (2002). Bactericidal activities of plant essential oils and some of their isolated constituents against Campylobacter jejuni, Escherichia coli, Listeria monocytogenes, and Salmonella enterica. Journal of Food Protection, 65, 1545–1560. [PubMed] [Google Scholar]

Astani A., Reichling J., & Schnitzler P. (2010). Comparative study on the antiviral activity of selected monoterpenes derived from essential oils. Phytotherapy Research, 24, 673–679. [PubMed] [Google Scholar]

Astani A., Reichling J., & Schnitzler P. (2011). Screening for antiviral activities of isolated compounds from essential oils. Evidence‐Based Complementary and Alternative Medicine: ECAM, 2011, 253643. [PMC free article] [PubMed] [Google Scholar]

Bakkali F., Averbeck S., Averbeck D., & Idaomar M. (2008). Biological effects of essential oils–a review. Food and Chemical Toxicology, 46, 446–475. [PubMed] [Google Scholar]

Bassole I. H., & Juliani H. R. (2012). Essential oils in combination and their antimicrobial properties. Molecules, 17, 3989–4006. [PMC free article] [PubMed] [Google Scholar]

Boivin G. (2013). Detection and management of antiviral resistance for influenza viruses. Influenza and Other Respiratory Viruses, 7, 18–23. [PMC free article] [PubMed] [Google Scholar]

Salari M. H., Amine G., Shirazi M. H., Hafezi R., & Mohammadypour M. (2006). Antibacterial effects of Eucalyptus globulusleaf extract on pathogenic bacteria isolated from specimens of patients with respiratory tract disorders. Clinical Microbiology & Infection, 12, 194–196. [PubMed] [Google Scholar]

Carson C. F., Hammer K. A., & Riley T. V. (2006). Melaleuca alternifolia (Tea Tree) oil: A review of antimicrobial and other medicinal properties. Clinical Microbiology Reviews, 19, 50–62.

Chen AE, Goldstein M, Carroll K, Song X, Perl TM, Siberry GK. Evolving epidemiology of pediatric Staphylococcus aureuscutaneous infections in a Baltimore hospital. Pediatr Emerg Care. 2006;22(10):717. doi: 10.1097/01.pec.0000236832.23947.a0. [PubMed] [CrossRef] [Google Scholar]

Hersh AL, Chambers HF, Maselli JH, Gonzales R. National trends in ambulatory visits and antibiotic prescribing for skin and soft-tissue infections. Arch Intern Med. 2008;168(14):1585–1591. doi: 10.1001/archinte.168.14.1585. [PubMed] [CrossRef] [Google Scholar]

Koerner R, Johnson AP. Changes in the classification and management of skin and soft tissue infections. J Antimicrob Chemother. 2011;66(2):232–234. doi: 10.1093/jac/dkq443. [PubMed] [CrossRef] [Google Scholar]

Guggenheim M, Zbinden R, Handschin AE, Gohritz A, Altintas MA, Giovanoli P. Changes in bacterial isolates from burn wounds and their antibiograms: A 20-year study (1986–2005) Burns. 2009;35(4):553–560. doi:
WHO (World Health Organisation) . (2014). Antimicrobial resistance: global report on surveillance.

Wu S., Patel K. B., Booth L. J., Metcalf J. P., Lin H. K., & Wu W. (2010). Protective essential oil attenuates influenza virus infection: An in vitro study in MDCK cells. BMC Complementary and Alternative Medicine, 10, 69. [PMC free article] [PubMed] [Google Scholar]

1016/j.burns.2008.09.004. [PubMed] [CrossRef] [Google Scholar]
]Stein RA. Antibiotic resistance: A global, interdisciplinary concern. The Am Biol Teacher. 2011;73(6):314–321. doi: 10.1525/abt.2011.73.6.3. [CrossRef] [Google Scholar]

Patwardhan B, Mashelkar RA. Traditional medicine-inspired approaches to drug discovery: can Ayurveda show the way forward? Drug Discov Today. 2009;14(15–16):804–811. [PubMed] [Google Scholar]

Saleem M, Nazir M, Ali MS, Hussain H, Lee YS, Riaz N, Jabbar A. Antimicrobial natural products: an update on future antibiotic drug candidates. Nat Prod Rep. 2010;27(2):238–254. doi: 10.1039/b916096e. [PubMed] [CrossRef] [Google Scholar]

Halcón L, Milkus K. Staphylococcus aureusand wounds: A review of tea tree oil as a promising antimicrobial. Am J Infect Con. 2004;32(7):402–408. doi: 10.1016/j.ajic.2003.12.008. [PubMed] [CrossRef] [Google Scholar]

Fisher K, Phillips C. Potential antimicrobial uses of essential oils in food: is citrus the answer? Trends Food Sci Technol. 2008;19(3):156–164. doi: 10.1016/j.tifs.2007.11.006. [CrossRef] [Google Scholar]

Cox S, Gustafson J, Mann C, Markham J, Liew Y, Hartland R, Bell H, Warmington J, Wyllie S. Tea tree oil causes K+ leakage and inhibits respiration in Escherichia coli. Lett Appl Microbiol. 1998;26:355–358. doi: 10.1046/j.1472-765X.1998.00348.x. [PubMed] [CrossRef] [Google Scholar]

Elsom GKF, Hide D. Susceptibility of methicillin-resistant Staphylococcus aureusto tea tree oil and mupirocin. J Antimicrob Chemother. 1999;43(3):427–428. doi: 10.1093/jac/43.3.427. [PubMed] [CrossRef] [Google Scholar]

May J, Chan CH, King A, Williams L, French GL. Time-kill studies of tea tree oils on clinical isolates. J Antimicrob Chemother. 2000;45(5):639–643. doi: 10.1093/jac/45.5.639. [PubMed] [CrossRef] [Google Scholar]

Takarada K, Kimizuka R, Takahashi N, Honma K, Okuda K, Kato T. A comparison of the antibacterial efficacies of essential oils against oral pathogens. Oral Microbiol Immunol. 2002;19:61–4. [PubMed] [Google Scholar]

Brady A, Loughlin R, Gilpin D, Kearney P, Tunney M. In vitro activity of tea-tree oil against clinical skin isolates of meticillin-resistant and -sensitive Staphylococcus aureusand coagulase-negative staphylococci growing planktonically and as biofilms. J Med Microbiol. 2006;55(10):1375–1380. doi: 10.1099/jmm.0.46558-0. [PubMed] [CrossRef] [Google Scholar]

O'Bryan CA, Crandall PG, Chalova VI, Ricke SC. Orange essential oils antimicrobial activities against Salmonella spp. J Food Sci. 2008;73(6):M264–M267. doi: 10.1111/j.1750-3841.2008.00790.x. [PubMed] [CrossRef] [Google Scholar]

Friedly EC, Crandall PG, Ricke SC, Roman M, O'Bryan C, Chalova VI. In vitro antilisterial effects of citrus oil fractions in combination with organic acids. J Food Sci. 2009;74(2):M67–M72. doi: 10.1111/j.1750-3841.2009.01056.x. [PubMed] [CrossRef] [Google Scholar]

Nannapaneni R, Chalova VI, Crandall PG, Ricke SC, Johnson MG, O'Bryan CA. Campylobacter and Arcobacter species sensitivity to commercial orange oil fractions. Int J Food Microbiol. 2009;129(1):43–49. doi: 10.1016/j.ijfoodmicro.2008.11.008. [PubMed] [CrossRef] [Google Scholar]

Muthaiyan A, Martin EM, Natesan S, Crandall PG, Wilkinson BJ, Ricke SC. Antimicrobial effect and mode of action of terpeneless cold-pressed Valencia orange essential oil on methicillin-resistant Staphylococcus aureus. J Appl Microbiol. 2012;112(5):1020–33. doi: 10.1111/j.1365-2672.2012.05270.x. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

Horsburgh MJ, Aish JL, White IJ, Shaw L, Lithgow JK, Foster SJ. sigmaB modulates virulence determinant expression and stress resistance: characterization of a functional rsbU strain derived from Staphylococcus aureus 8325–4. J Bacteriol. 2002;184(19):5457–67. doi: 10.1128/JB.184.19.5457-5467.2002. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

Kuroda M, Ohta T, Uchiyama I, Baba T, Yuzawa H, Kobayashi I, Cui L, Oguchi A, Aoki K, Nagai Y. Whole genome sequencing of meticillin-resistant Staphylococcus aureus. Lancet. 2001;357(9264):1225–1240. doi: 10.1016/S0140-6736(00)04403-2. [PubMed] [CrossRef] [Google Scholar]

Pfeltz RF, Singh VK, Schmidt JL, Batten MA, Baranyk CS, Nadakavukaren MJ, Jayaswal RK, Wilkinson BJ. Characterization of passage-selected vancomycin-resistant Staphylococcus aureusstrains of diverse parental backgrounds. Antimicrob Agents Chemother. 2000;44(2):294–303. doi: 10.1128/AAC.44.2.294-303.2000. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

Braddock RJ. Handbook of citrus by-products and processing technology. Willey, model. Burns. 2004;30(8):772–777. doi: 10.1016/j.burns.2004.06.006. [PubMed] [CrossRef] [Google Scholar]

Dorman HJD, Deans SG. Antimicrobial agents from plants: antibacterial activity of plant volatile oils. J Appl Microbiol. 2000;88(2):308–316. doi: 10.1046/j.1365-2672.2000.00969.x. [PubMed] [CrossRef] [Google Scholar]

Dryden MS, Dailly S, Crouch M. A randomized, controlled trial of tea tree topical preparations versus a standard topical regimen for the clearance of MRSA colonization. J Hosp Infect. 2004;56(4):283–286. doi: 10.1016/j.jhin.2004.01.008. [PubMed] [CrossRef] [Google Scholar]

Sherry E, Boeck H, Warnke P. Percutaneous treatment of chronic MRSA osteomyelitis with a novel plant-derived antiseptic. BMC Surgery. 2001;1(1):1. doi: 10.1186/1471-2482-1-1. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

Sherry E, Boeck H, Warnke PH. Topical application of a new formulation of eucalyptus oil phytochemical clears methicillin-resistant Staphylococcus aureusAm J Infect Control. 2001;29(5):346–346. doi: 10.1067/mic.2001.117403. [PubMed] [CrossRef] [Google Scholar]

Palaniappan K, Holley RA. Use of natural antimicrobials to increase antibiotic susceptibility of drug resistant bacteria. Int J Food Microbiol. 2010;140(2–3):164–168. [PubMed] [Google Scholar]

anisumAnalytica Chimica Acta. 2005;530(1):155–161. [Google Scholar]
Gulcin I, Oktay M, Kirecci E, Kufrevioglu OI. Screening of antioxidant and antimicrobial activities of anise (Pimpinella anisum) seed extracts. Food Chemistry. 2003;83(3):371–382. [Google Scholar]

Embong MB, Hadziyev D, Molnar S. Essential oils from spices grown in Alberta. Anise oil (Pimpinella anisumCanadian Journal of Plant Science. 1997;57:681–688. [Google Scholar]

Fujimatu E, Ishikawa T, Kitajima J. Aromatic compound glucosides, alkyl glucoside and glucide from the fruit of anise. Phytochemistry. 2003;63(5):609–616. [PubMed] [Google Scholar]

Chaudhry NM, Tariq P. Bactericidal activity of black pepper, bay leaf, aniseed and coriander against oral isolates. Pakistan Journal of Pharmaceutical Sciences. 2006;19(3):214–218. [PubMed] [Google Scholar]

Shukla HS, Tripathi SC. Antifungal substance in the essential oil of anise (Pimpinella anisumUltural and Biological Chemistry. 1987;51(7):1991–1993. [Google Scholar]

Kosalec I, Pepeljnjak S, Kuatrak D. Antifungal activity of fluid extract and essential oil from anise fruits (Pimpinella anisum, Apiaceae) Acta Pharmaceutica. 2005;55(4):377–385. [PubMed] [Google Scholar]

Yazdani D, Rezazadeh S, Amin G, Zainal Abidin MA, Shahnazi S, Jamalifar H. Antifungal activity of dried extracts of anise (Pimpinella anisum) and star anise (Illicium verum Hook, f.) against dermatophyte and saprophyte fungi. Journal of Medicinal Plants. 2009;8(5):24–29. [Google Scholar]

anococcygeus smooth muscle. Journal of Ethnopharmacology. 2007;110(1):23– [PubMed] [Google Scholar]

Pourgholami MH, Majzoob S, Javadi M, Kamalinejad M, Fanaee GHR, Sayyah M. The fruit essential oil of Pimpinella anisum exerts anticonvulsant effects in mice. Journal of Ethnopharmacology. 1999;66(2):211–215. [PubMed] [Google Scholar]
  1. Heidari MR, Ayeli M. Effects of methyl alcoholic extract of Pimpinella anisum on picrotoxin induced seizure in mice and its probable mechanism. Scientific Journal of Kurdistan University of Medical Science. 2005;10(3):1–8. [Google Scholar]
  2. Abdul-Ghani AS, El-Lati SG, Sacaan AI. Anticonvulsant effects of some Arab medicinal plants. International Journal of Crude Drug Research. 1987;25(1):39– [Google Scholar


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